Risk factors for cancer in hereditary pancreatitis

被引：137

作者：

Lowenfels, AB ^{[1
]}

Maisonneuve, P

Whitcomb, DC

机构：

[1] New York Med Coll, Dept Surg, Valhalla, NY 10595 USA

[2] New York Med Coll, Dept Community & Prevent Med, Valhalla, NY 10595 USA

[3] European Inst Oncol, Div Epidemiol & Biostat, Milan, Italy

[4] Univ Pittsburgh, Dept Med, Pittsburgh, PA USA

来源：

MEDICAL CLINICS OF NORTH AMERICA | 2000年 / 84卷 / 03期

关键词：

D O I：

10.1016/S0025-7125(05)70240-6

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Hereditary pancreatitis accounts for approximately 1% of all types of chronic pancreatitis. The cumulative lifetime risk of pancreatic cancer in this genetic disorder is estimated to be approximately 30%. The high risk of pancreatic cancer in this genetic disorder may be related to the prolonged duration of pancreatitis, allowing for the gradual transmission of a normal to fibrotic, dysfunctional organ.

引用

页码：565 / +

页数：10

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