Mutation in hepatocyte nuclear factor-1 beta gene (TCF2) associated with MODY

被引：688

作者：

Horikawa, Y

Iwasaki, N

Hara, M

Furuta, H

Hinokio, Y

Cockburn, BN

Lindner, T

Yamagata, K

Ogata, M

Tomonaga, O

Kuroki, H

Kasahara, T

Iwamoto, Y

Bell, GI

机构：

[1] UNIV CHICAGO,HOWARD HUGHES MED INST,CHICAGO,IL 60637

[2] UNIV CHICAGO,DEPT BIOCHEM & MOL BIOL,CHICAGO,IL 60637

[3] UNIV CHICAGO,DEPT MED,CHICAGO,IL 60637

[4] TOKYO WOMENS MED COLL,CTR DIABET,SHINJUKU KU,TOKYO 162,JAPAN

[5] JOUSAI HOSP,DEPT MED,TOKYO 167,JAPAN

来源：

NATURE GENETICS | 1997年 / 17卷 / 04期

关键词：

D O I：

10.1038/ng1297-384

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

引用

页码：384 / 385

页数：2

共 13 条

[1] MORE POTENT TRANSCRIPTIONAL ACTIVATORS OR A TRANSDOMINANT INHIBITOR OF THE HNF1 HOMEOPROTEIN FAMILY ARE GENERATED BY ALTERNATIVE RNA PROCESSING
BACH, I
YANIV, M
[J]. EMBO JOURNAL, 1993, 12 (11) : 4229 - 4242
[2] GENE FOR NON-INSULIN-DEPENDENT DIABETES-MELLITUS (MATURITY-ONSET DIABETES OF THE YOUNG SUBTYPE) IS LINKED TO DNA POLYMORPHISM ON HUMAN CHROMOSOME-20Q
BELL, GI
XIANG, KS
NEWMAN, MV
WU, SH
WRIGHT, LG
FAJANS, SS
SPIELMAN, RS
COX, NJ
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (04) : 1484 - 1488
[3] Liver-enriched transcription factors and hepatocyte differentiation
Cereghini, S
[J]. FASEB JOURNAL, 1996, 10 (02) : 267 - 282
[4] CITRON BA, 1993, AM J HUM GENET, V53, P768
[5] Organization and partial sequence of the hepatocyte nuclear factor-4 alpha MODY1 gene and identification of a missense mutation, R127W, in a Japanese family with MODY
Furuta, H
Iwasaki, N
Oda, N
Hinokio, Y
Horikawa, Y
Yamagata, K
Yano, N
Sugahiro, J
Ogata, M
Ohgawara, H
Omori, Y
Iwamoto, Y
Bell, GI
[J]. DIABETES, 1997, 46 (10) : 1652 - 1657
[6] A genome-wide search for human non-insulin dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2
Hanis, CL
Boerwinkle, E
Chakraborty, R
Ellsworth, DL
Concannon, P
Stirling, B
Morrison, VA
Wapelhorst, B
Spielman, RS
GogolinEwens, KJ
Shephard, JM
Williams, SR
Risch, N
Hinds, D
Iwasaki, N
Ogata, M
Omori, Y
Petzold, C
Rietzsch, H
Schroder, HE
Schulze, J
Cox, NJ
Menzel, S
Boriraj, VV
Chen, X
Lim, LR
Lindner, T
Mereu, LE
Wang, YQ
Xiang, K
Yamagata, K
Yang, Y
Bell, GI
[J]. NATURE GENETICS, 1996, 13 (02) : 161 - 166
[7] Mutations in the hepatocyte nuclear factor-1 alpha/MODY3 gene in Japanese subjects with early- and late-onset NIDDM
Iwasaki, N
Oda, N
Ogata, M
Hara, M
Hinokio, Y
Oda, Y
Yamagata, K
Kanematsu, S
Ohgawara, H
Omori, Y
Bell, GI
[J]. DIABETES, 1997, 46 (09) : 1504 - 1508
[8] LAZZARO D, 1992, DEVELOPMENT, V114, P469
[9] CHARACTERIZATION OF A COFACTOR THAT REGULATES DIMERIZATION OF A MAMMALIAN HOMEODOMAIN PROTEIN
MENDEL, DB
KHAVARI, PA
CONLEY, PB
GRAVES, MK
HANSEN, LP
ADMON, A
CRABTREE, GR
[J]. SCIENCE, 1991, 254 (5039) : 1762 - 1767
[10] HNF-1-ALPHA AND HNF-1-BETA (VHNF-1) SHARE DIMERIZATION AND HOMEO DOMAINS, BUT NOT ACTIVATION DOMAINS, AND FORM HETERODIMERS INVITRO
MENDEL, DB
HANSEN, LP
GRAVES, MK
CONLEY, PB
CRABTREE, GR
[J]. GENES & DEVELOPMENT, 1991, 5 (06) : 1042 - 1056

← 1 2 →