Regulators of PP2C Phosphatase Activity Function as Abscisic Acid Sensors

被引：1876

作者：

Ma, Yue ^{[1
]}

Szostkiewicz, Izabela ^{[1
]}

Korte, Arthur ^{[1
]}

Moes, Daniele ^{[1
]}

Yang, Yi ^{[1
]}

Christmann, Alexander ^{[1
]}

Grill, Erwin ^{[1
]}

机构：

[1] Tech Univ Munich, Lehrstuhl Bot, D-85354 Freising Weihenstephan, Germany

来源：

SCIENCE | 2009年 / 324卷 / 5930期

关键词：

EARLY SEEDLING DEVELOPMENT; CRYSTAL-STRUCTURE; ABA CONTROL; ARABIDOPSIS; PROTEIN; ABI1; GERMINATION; RECEPTOR; SIGNAL; TRANSDUCTION;

D O I：

10.1126/science.1172408

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The plant hormone abscisic acid (ABA) acts as a developmental signal and as an integrator of environmental cues such as drought and cold. Key players in ABA signal transduction include the type 2C protein phosphatases (PP2Cs) ABI1 and ABI2, which act by negatively regulating ABA responses. In this study, we identify interactors of ABI1 and ABI2, which we have named regulatory components of ABA receptor (RCARs). In Arabidopsis, RCARs belong to a family with 14 members that share structural similarity with class 10 pathogen-related proteins. RCAR1 was shown to bind ABA, to mediate ABA-dependent inactivation of ABI1 or ABI2 in vitro, and to antagonize PP2C action in planta. Other RCARs also mediated ABA-dependent regulation of ABI1 and ABI2, consistent with a combinatorial assembly of receptor complexes.

引用

页码：1064 / 1068

页数：5

共 31 条

[1] ABA is an essential signal for plant resistance to pathogens affecting JA biosynthesis and the activation of defenses in Arabidopsis [J].

Adie, Bruce A. T. ;

Perez-Perez, Julian ;

Perez-Perez, Manuel M. ;

Godoy, Marta ;

Sanchez-Serrano, Jose-J. ;

Schmelz, Eric A. ;

Solano, Roberto .

PLANT CELL, 2007, 19 (05) :1665-1681

[2] A flagellin-induced complex of the receptor FLS2 and BAK1 initiates plant defence [J].

Chinchilla, Delphine ;

Zipfel, Cyril ;

Robatzek, Silke ;

Kemmerling, Birgit ;

Nuernberger, Thorsten ;

Jones, Jonathan D. G. ;

Felix, Georg ;

Boller, Thomas .

NATURE, 2007, 448 (7152) :497-U12

[3] A hydraulic signal in root-to-shoot signalling of water shortage [J].

Christmann, Alexander ;

Weiler, Elmar W. ;

Steudle, Ernst ;

Grill, Erwin .

PLANT JOURNAL, 2007, 52 (01) :167-174

[4] Lupinus luteus pathogenesis-related protein as a reservoir for cytokinin [J].

Fernandes, Humberto ;

Pasternak, Oliwia ;

Bujacz, Grzegorz ;

Bujacz, Anna ;

Sikorski, Michal M. ;

Jaskolski, Mariusz .

JOURNAL OF MOLECULAR BIOLOGY, 2008, 378 (05) :1040-1051

[5] Genetic characterization reveals no role for the reported ABA receptor, GCR2, in ABA control of seed germination and early seedling development in Arabidopsis [J].

Gao, Yajun ;

Zeng, Qingning ;

Guo, Jianjun ;

Cheng, Jia ;

Ellis, Brian E. ;

Chen, Jin-Gui .

PLANT JOURNAL, 2007, 52 (06) :1001-1013

[6] The GCR2 Gene Family Is Not Required for ABA Control of Seed Germination and Early Seedling Development in Arabidopsis [J].

Guo, Jianjun ;

Zeng, Qingning ;

Emami, Mohammad ;

Ellis, Brian E. ;

Chen, Jin-Gui .

PLOS ONE, 2008, 3 (08)

[7] A calcium sensor and its interacting protein kinase are global regulators of abscisic acid signaling in Arabidopsis [J].

Guo, Y ;

Xiong, LM ;

Song, CP ;

Gong, DM ;

Halfter, U ;

Zhu, JK .

DEVELOPMENTAL CELL, 2002, 3 (02) :233-244

[8] Homeodomain protein ATHB6 is a target of the protein phosphatase ABI1 and regulates hormone responses in Arabidopsis [J].

Himmelbach, A ;

Hoffmann, T ;

Leube, M ;

Höhener, B ;

Grill, E .

EMBO JOURNAL, 2002, 21 (12) :3029-3038

[9] Perception and transduction of abscisic acid signals: keys to the function of the versatile plant hormone ABA [J].

Hirayama, Takashi ;

Shinozaki, Kazuo .

TRENDS IN PLANT SCIENCE, 2007, 12 (08) :343-351

[10] Comment on "A G protein-coupled receptor is a plasma membrane receptor for the plant hormone abscisic acid" [J].

Johnston, Christopher A. ;

Temple, Brenda R. ;

Chen, Jin-Gui ;

Gao, Yajun ;

Moriyama, Etsuko N. ;

Jones, Alan M. ;

Siderovski, David P. ;

Willard, Francis S. .

SCIENCE, 2007, 318 (5852) :914c

← 1 2 3 4 →