The coccidian oocyst: a tough nut to crack!

被引:123
作者
Belli, Sabina I. [1 ]
Smith, Nicholas C.
Ferguson, David J. P.
机构
[1] Univ Technol Sydney, Inst Biotechnol Infect Dis, Sydney, NSW 2007, Australia
[2] Univ Oxford, John Radcliffe Hosp, Nuffield Dept Pathol, Oxford OX3 9DU, England
基金
英国惠康基金;
关键词
D O I
10.1016/j.pt.2006.07.004
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
Coccidian parasites are transmitted between hosts by the ingestion of food or water contaminated with oocysts, followed by the release of infectious sporozoites and invasion of the gastro-intestinal tract. In the external environment, sporozoites are protected from desiccation and chemical disinfection by the oocyst wall. This unique structure guarantees successful disease transmission and is as vital to the coccidian parasite as the exoskeleton is to insects - without it they would die. Here, we revisit the early work and combine it with newer molecular data to describe our present understanding of the coccidian oocyst wall.
引用
收藏
页码:416 / 423
页数:8
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