Scleroderma-like reaction induced by uracil-tegafur (UFT), a second-generation anticancer agent

被引：21

作者：

Kono, T

Ishii, M

Negoro, N

Taniguchi, S

机构：

[1] Osaka City Univ, Sch Med, Dept Dermatol, Abeno Ku, Osaka 5458585, Japan

[2] Osaka City Univ, Sch Med, Dept Internal Med 1, Abeno Ku, Osaka 5458585, Japan

[3] Osaka Gen Hosp, Dept Dermatol, W Japan Railway Co, Osaka, Japan

来源：

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY | 2000年 / 42卷 / 03期

关键词：

D O I：

10.1016/S0190-9622(00)90233-0

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

UFT, a combination of uracil and tegafur, is a second-generation anticancer agent. UFT has been used in Japan, other Asian countries, South America, and Russia. Recently, UFT has been extensively studied for colorectal pancreatic, and various types of cancer in North America and Europe, especially with leukovorin. We report a case of a scleroderma-like reaction induced by long-term administration of UFT. This is the first report of UFT-induced scleroderma-like reaction.

引用

页码：519 / 520

页数：2

共 5 条

[1] A phase I and pharmacokinetic study of oral uracil, ftorafur, and leucovorin in patients with advanced cancer [J].