Mediating mismatch repair

被引：59

作者：

Jiricny, J ^{[1
]}

机构：

[1] Univ Zurich, Inst Med Radiobiol, CH-8008 Zurich, Switzerland

[2] Paul Scherrer Inst, CH-8048 Zurich, Switzerland

来源：

NATURE GENETICS | 2000年 / 24卷 / 01期

关键词：

D O I：

10.1038/71698

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The DNA repair picture in humans becomes more complete with the identification of MLH3, a homologue of MutL and a heterodimeric partner of MLH1.

引用

页码：6 / 8

页数：3

共 15 条

[1] Involvement of the mismatch repair system in temozolomide-induced apoptosis [J].

D'Atri, S ;

Tentori, L ;

Lacal, PM ;

Graziani, G ;

Pagani, E ;

Benincasa, E ;

Zambruno, G ;

Bonmassar, E ;

Jiricny, J .

MOLECULAR PHARMACOLOGY, 1998, 54 (02) :334-341

[2] Mismatch-, MutS-, MutL-, and helicase II-dependent unwinding from the single-strand break of an incised heteroduplex [J].

Dao, V ;

Modrich, P .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (15) :9202-9207

[3] HNPCC-like cancer predisposition in mice through simultaneous loss of Msh3 and MSh6 mismatch-repair protein functions [J].

de Wind, N ;

Dekker, M ;

Claij, N ;

Jansen, L ;

van Klink, Y ;

Radman, M ;

Riggins, G ;

van der Valk, M ;

van 't Wout, K ;

Riele, HT .

NATURE GENETICS, 1999, 23 (03) :359-362

[4] hMutSα- and hMutLα-dependent phosphorylation of p53 in response to DNA methylator damage [J].

Duckett, DR ;

Bronstein, SM ;

Taya, Y ;

Modrich, P .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (22) :12384-12388

[5] Mutation in the mismatch repair gene Msh6 causes cancer susceptibility [J].

Edelmann, W ;

Yang, K ;

Umar, A ;

Heyer, J ;

Lau, K ;

Fan, KH ;

Liedtke, W ;

Cohen, PE ;

Kane, MF ;

Lipford, JR ;

Yu, NJ ;

Crouse, GF ;

Pollard, JW ;

Kunkel, T ;

Lipkin, M ;

Kolodner, R ;

Kucherlapati, R .

CELL, 1997, 91 (04) :467-477

[6] The Saccharomyces cerevisiae MLH3 gene functions in MSH3-dependent suppression of frameshift mutations [J].

Flores-Rozas, H ;

Kolodner, RD .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (21) :12404-12409

[7] Role of DNA mismatch repair and p53 in signaling induction of apoptosis by alkylating agents [J].

Hickman, MJ ;

Samson, LD .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (19) :10764-10769

[8] Replication errors: cha(lle)nging the genome [J].

Jiricny, J .

EMBO JOURNAL, 1998, 17 (22) :6427-6436

[9]

Kolodner RD, 1999, CANCER RES, V59, P5068

[10] NUCLEOTIDE REPEATS - SLIPPERY DNA AND DISEASES [J].

KUNKEL, TA .

NATURE, 1993, 365 (6443) :207-208

← 1 2 →