Alveolar Epithelium: Beyond the Barrier

被引：14

作者：

Borok, Zea ^{[1
]}

机构：

[1] Univ So Calif, Will Rogers Inst Pulm Res Ctr, Keck Sch Med, Dept Med,Div Pulm Crit Care & Sleep Med, Los Angeles, CA 90089 USA

来源：

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY | 2014年 / 50卷 / 05期

基金：

美国国家卫生研究院;

关键词：

IDIOPATHIC PULMONARY-FIBROSIS; ENDOPLASMIC-RETICULUM STRESS; ACTIVE ION-TRANSPORT; MESENCHYMAL TRANSITION; I CELLS; PRIMARY CULTURE; EXPRESSION; PHENOTYPE; SODIUM; CATENIN;

D O I：

10.1165/rcmb.2014-0089PS

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

I am deeply honored to have been awarded an American Thoracic Society Recognition Award for Scientific Accomplishment for 2014. Over the last 20 years, it has become clear that the alveolar epithelium, my area of research focus, is not simply a gas exchange surface and barrier to leakage of fluid and protein into the alveoli, but is an active participant in the pathogenesis of a number of lung diseases, including pulmonary fibrosis. Recognition by this Award stimulates a review of the awardee's contributions to the field, as summarized in this perspective.

引用

页码：853 / 856

页数：4

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