Application of palladium-catalyzed Pd-aryl/P-aryl exchanges: preparation of functionalized aryl phosphines by phosphination of aryl bromides using triarylphosphines

被引：41

作者：

Kwong, FY ^{[1
]}

Lai, CW ^{[1
]}

Yu, M ^{[1
]}

Chan, KS ^{[1
]}

机构：

[1] Chinese Univ Hong Kong, Dept Chem, Open Lab Chirotechnol, Inst Mol Technol Drug Discovery & Synth, Shatin, Hong Kong, Peoples R China

来源：

TETRAHEDRON | 2004年 / 60卷 / 26期

关键词：

phosphination; palladium; triphenylphosphine; triarylphosphine; cross-coupling; catalysis;

D O I：

10.1016/j.tet.2004.04.085

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Palladium-catalyzed Pd-aryl/P-aryl interchange reaction was applied in the synthesis of various functionalized arylphosphines. This phosphination used inexpensive, readily available and air stable triarylphosphines as the phosphinating agents. Broad functional groups were compatible including keto, aldehyde, ester, nitrile, ether, chloride, pyridyl and thiophenyl groups. Halides were found to be good promoter for the rates and yields of the reaction. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：5635 / 5645

页数：11

共 98 条

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