Tetramethylpyridiniumporphyrazines -: a new class of G-quadruplex inducing and stabilising ligands

被引:124
作者
Goncalves, Diana P. N. [1 ]
Rodriguez, Raphael [1 ]
Balasubramanian, Shankar [1 ]
Sanders, Jeremy K. M. [1 ]
机构
[1] Univ Cambridge, Chem Lab, Cambridge CB2 1EW, England
关键词
D O I
10.1039/b611731g
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
3,4-Tetramethylpyridiniumporphyrazines bind strongly and selectively to human telomeric G-quadruplex DNA, inducing the formation of an antiparallel quadruplex in a process that mimics molecular chaperones.
引用
收藏
页码:4685 / 4687
页数:3
相关论文
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