The organization of collagen in the corneal stroma

被引：181

作者：

Meek, KM ^{[1
]}

Boote, C ^{[1
]}

机构：

[1] Univ Wales Coll Cardiff, Dept Optometry & Vis Sci, Struct Biophys Grp, Cardiff CF10 3NB, S Glam, Wales

来源：

EXPERIMENTAL EYE RESEARCH | 2004年 / 78卷 / 03期

基金：

英国惠康基金; 英国医学研究理事会;

关键词：

cornea; stroma; limbus; collagen; proteoglycans; X-ray diffraction; microscopy;

D O I：

10.1016/j.exer.2003.07.003

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

The cornea has evolved to fulfil the dual functions of enclosing and protecting the inner contents of the eye, and focussing light onto the retina with minimum scatter and optical degradation. It does this by means of the arrangement of the constituent collagen fibrils, an arrangement that is unique in connective tissues. This article reviews our current knowledge about the detailed organization of collagen in the corneal stroma, and presents new data suggesting that a significant proportion of collagen fibrils running across the cornea, change direction near the limbus and fuse with the circumferential limbal collagen. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：503 / 512

页数：10

共 62 条

[1] Three-dimensional reconstructions of extracellular matrix polymers using automated electron tomography [J].