Cancer cell biology: Myc wins the competition

被引:22
作者
Donaldson, TD [1 ]
Duronio, RJ
机构
[1] Univ N Carolina, Lineberger Comprehens Canc Ctr, Chapel Hill, NC 27599 USA
[2] Univ N Carolina, Dept Biol, Chapel Hill, NC 27599 USA
[3] Univ N Carolina, Program Mol Biol & Biotechnol, Chapel Hill, NC 27599 USA
关键词
D O I
10.1016/j.cub.2004.05.035
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
During Drosophila development, cells with elevated levels of the Myc oncoprotein grow faster than, and induce cell death in, nearby wild-type cells, suggesting how inappropriate Myc over-expression provides cells with a competitive advantage that can lead to cancer.
引用
收藏
页码:R425 / R427
页数:3
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