An event-related potential study an the impairment of automatic processing of auditory input in schizophrenia

被引：46

作者：

Shutara, Y ^{[1
]}

Koga, Y ^{[1
]}

Fujita, K ^{[1
]}

Takeuchi, H ^{[1
]}

Mochida, M ^{[1
]}

Takemasa, K ^{[1
]}

机构：

[1] KYORIN UNIV, SCH MED, DEPT NEUROPSYCHIAT, MITAKA, TOKYO 181, JAPAN

来源：

BRAIN TOPOGRAPHY | 1996年 / 8卷 / 03期

关键词：

event-related potential (ERP); schizophrenia; auditory input; P300; mismatch negativity (MMN); Brief Psychiatric Rating Scale (BPRS);

D O I：

10.1007/BF01184786

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Mismatch negativity (MMN) and P300 to auditory stimuli was carried out using global field power (GFP) in 25 schizophrenics and 25 normal controls. The peak latencies of MMN and P300 were significantly longer in schizophrenics than in normal controls, and the differences in MMN were marked in the frontal regions. The peak amplitudes of MMN and P300 were significantly smaller in schizophrenics. The scalp distribution of MMN to 1050 Hz tone differed between the two groups, although that to 1100 Hz was similar to each other. The results indicate an impairment in the automatic discrimination process of auditory input in schizophrenics.

引用

页码：285 / 289

页数：5

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