Pharmacological options in the treatment of benign prostatic hyperplasia

被引：162

作者：

Kenny, B ^{[1
]}

Ballard, S ^{[1
]}

Blagg, J ^{[1
]}

Fox, D ^{[1
]}

机构：

[1] PFIZER LTD,CENT RES,DEPT DISCOVERY CHEM,SANDWICH CT13 9NJ,KENT,ENGLAND

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1997年 / 40卷 / 09期

关键词：

D O I：

10.1021/jm960697s

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

[No abstract available]

引用

页码：1293 / 1315

页数：23

共 156 条

[1]

ABELL AD, 1995, CURR MED CHEM, V2, P583

[2] A NONSTEROIDAL DIENE ACID INHIBITOR OF HUMAN TYPE-2 STEROID 5-ALPHA-REDUCTASE [J].

ABELL, AD ;

BRANDT, M ;

LEVY, MA ;

HOLT, DA .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1994, 4 (19) :2327-2330

[3] CAN FINASTERIDE REVERSE THE PROGRESS OF BENIGN PROSTATIC HYPERPLASIA - A 2-YEAR PLACEBO-CONTROLLED STUDY [J].

ANDERSEN, JT ;

EKMAN, P ;

WOLF, H ;

BEISLAND, HO ;

JOHANSSON, JE ;

KONTTURI, M ;

LEHTONEN, T ;

TVETER, K ;

BODKER, A ;

VEDEL, O ;

NORDLING, J ;

POULSEN, AL ;

SCHOU, J ;

HVIDT, V ;

HANSEN, JB ;

MEYHOFF, HH ;

ELDRUP, J ;

HARTWELL, D ;

COLSTRUP, H ;

LYNGDORF, P ;

NIELSEN, AH ;

LARSEN, E ;

WALTER, S ;

LARSEN, EH ;

THYBO, E ;

MOMMSEN, S ;

BROK, KE ;

PALM, L ;

GENSTER, H ;

ANDERSEN, M ;

KAUPPINEN, P ;

RAUVALA, M ;

HAKKINEN, J ;

TAMMELA, T ;

TAINIO, H ;

HYNNINEN, O ;

TIITINEN, J ;

LEHTORANTA, K ;

ALAOPAS, M ;

PERTTILA, I ;

PETAS, A ;

RINTALA, E ;

SALMINEN, R ;

JUUSELA, H ;

HANSSON, E ;

VONWENDT, R ;

TUHKANEN, K ;

TALJA, M ;

NURMI, M ;

PUNTALA, P .

UROLOGY, 1995, 46 (05) :631-637

[4] DELETION OF STEROID 5-ALPHA-REDUCTASE 2-GENE IN MALE PSEUDOHERMAPHRODITISM [J].

ANDERSSON, S ;

BERMAN, DM ;

JENKINS, EP ;

RUSSELL, DW .

NATURE, 1991, 354 (6349) :159-161

[5]

ANDERSSON S, 1990, P NATL ACAD SCI USA, V87, P8640

[6]

ANDERSSON S, 1991, Patent No. 17251

[7]

ANDREWS RC, 1996, Patent No. 16049

[8] SYNTHESIS AND HYPOTENSIVE ACTIVITY OF BENZAMIDOPIPERIDYLETHYLINDOLES [J].

ARCHIBALD, JL ;

ALPS, BJ ;

CAVALLA, JF ;

JACKSON, JL .

JOURNAL OF MEDICINAL CHEMISTRY, 1971, 14 (11) :1054-+

[9]

AUDET P, 1993, CLIN PHARMACOL THER, V53, P231

[10] 4-AZA-3-OXO-5-ALPHA-ANDROST-1-ENE-17-BETA-N-ARYL-CARBOXAMIDES AS DUAL INHIBITORS OF HUMAN TYPE-1 AND TYPE-2 STEROID 5-ALPHA-REDUCTASES - DRAMATIC EFFECT OF N-ARYL SUBSTITUENTS ON TYPE-1 AND TYPE-2 5-ALPHA-REDUCTASE INHIBITORY POTENCY [J].

BAKSHI, RK ;

RASMUSSON, GH ;

PATEL, GF ;

MOSLEY, RT ;

CHANG, B ;

ELLSWORTH, K ;

HARRIS, GS ;

TOLMAN, RL .

JOURNAL OF MEDICINAL CHEMISTRY, 1995, 38 (17) :3189-3192

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