Selective reduction of the posterior superior vermis in men with chronic schizophrenia

被引:54
作者
Okugawa, G [5 ]
Sedvall, G
Nordström, M
Andreasen, N
Pierson, R
Magnotta, V
Agartz, I
机构
[1] Kansai Med Univ, Dept Neuropsychiat, Osaka 5708506, Japan
[2] Swedish Inst Comp Sci, SE-16429 Kista, Sweden
[3] Univ Iowa, Coll Med, Mental Hlth Clin Res Ctr, Iowa City, IA 52242 USA
[4] Univ Iowa Hosp & Clin, Iowa City, IA 52242 USA
[5] Karolinska Hosp & Inst, Dept Clin Neurosci, Psychiat Sect, Human Brain Informat Ctr,HUBIN, SE-17176 Stockholm, Sweden
关键词
cerebellum; MRI; schizophrenia; segmentation; posterior superior vermis;
D O I
10.1016/S0920-9964(01)00248-1
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Cerebellar structures were measured in 30 chronic schizophrenic men and 18 healthy men using high resolution MRI. The volume of the posterior superior vermis was found to be significantly smaller in the schizophrenic men, but there was no difference in other cerebellar regions or the intracranial volume. The findings support the view that within the cerebellum the posterior superior vermis may be selectively reduced in men with chronic schizophrenia. (C) 2002 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:61 / 67
页数:7
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