Tumor-Suppressive microRNAs in Lung Cancer: Diagnostic and Therapeutic Opportunities

被引：13

作者：

Sempere, Lorenzo F. ^{[1
]}

Liu, Xi ^{[2
]}

Dmitrovsky, Ethan ^{[1
,2
,3
]}

机构：

[1] Dartmouth Hitchcock Med Ctr, Dept Med, Lebanon, NH 03766 USA

[2] Dartmouth Hitchcock Med Ctr, Dept Pharmacol & Toxicol, Lebanon, NH 03766 USA

[3] Dartmouth Hitchcock Med Ctr, Norris Cotton Canc Ctr, Lebanon, NH 03766 USA

来源：

THESCIENTIFICWORLDJOURNAL | 2009年 / 9卷

基金：

美国国家卫生研究院;

关键词：

microRNA; (miRNA; miR); lung cancer; expression profiling; in situ hybridization; miR-34c; miR-142-5p; miR145; cyclin E;

D O I：

10.1100/tsw.2009.88

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

[No abstract available]

引用

页码：626 / 628

页数：3

共 11 条

[1] MicroRNAs and cancer: Profile, profile, profile [J].

Barbarotto, Elisa ;

Schmittgen, Thomas D. ;

Calin, George A. .

INTERNATIONAL JOURNAL OF CANCER, 2008, 122 (05) :969-977

[2] Origins and Mechanisms of miRNAs and siRNAs [J].

Carthew, Richard W. ;

Sontheimer, Erik J. .

CELL, 2009, 136 (04) :642-655

[3] microRNAs join the p53 network - another piece in the tumour-suppression puzzle [J].

He, Lin ;

He, Xingyue ;

Lowe, Scott W. ;

Hannon, Gregory J. .

NATURE REVIEWS CANCER, 2007, 7 (11) :819-822

[4]

Kauppinen S, 2006, HANDB EXP PHARM, V173, P405

[5] Suppression of non-small cell lung tumor development by the let-7 microRNA family [J].

Kumar, Madhu S. ;

Erkeland, Stefan J. ;

Pester, Ryan E. ;

Chen, Cindy Y. ;

Ebert, Margaret S. ;

Sharp, Phillip A. ;

Jacks, Tyler .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2008, 105 (10) :3903-3908

[6] Uncovering Growth-Suppressive MicroRNAs in Lung Cancer [J].

Liu, Xi ;

Sempere, Lorenzo F. ;

Galimberti, Fabrizio ;

Freemantle, Sarah J. ;

Black, Candice ;

Dragnev, Konstantin H. ;

Ma, Yan ;

Fiering, Steven ;

Memolii, Vincent ;

Li, Hua ;

DiRenzo, James ;

Korc, Murray ;

Cole, Charles N. ;

Bak, Mads ;

Kauppinen, Sakari ;

Dmitrovsky, Ethan .

CLINICAL CANCER RESEARCH, 2009, 15 (04) :1177-1183

[7] Transgenic cyclin E triggers dysplasia and multiple pulmonary adenocarcinomas [J].

Ma, Yan ;

Fiering, Steven ;

Black, Candice ;

Liu, Xi ;

Yuan, Ziqiang ;

Memoli, Vincent A. ;

Robbins, David J. ;

Bentley, Heather A. ;

Tsongalis, Gregory J. ;

Demidenko, Eugene ;

Freemantle, Sarah J. ;

Dmitrovsky, Ethan .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (10) :4089-4094

[8] MicroRNA Silencing in Primates: Towards Development of Novel Therapeutics [J].

Petri, Andreas ;

Lindow, Morten ;

Kauppinen, Sakari .

CANCER RESEARCH, 2009, 69 (02) :393-395

[9] p53 represses c-Myc through induction of the tumor suppressor miR-145 [J].

Sachdeva, Mohit ;

Zhu, Shoumin ;

Wu, Fangting ;

Wu, Hailong ;

Walia, Vijay ;

Kumar, Sumit ;

Elble, Randolph ;

Watabe, Kounosuke ;

Mo, Yin-Yuan .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2009, 106 (09) :3207-3212

[10] Altered microRNA expression confined to specific epithelial cell Subpopulations in breast cancer [J].

Sempere, Lorenzo F. ;

Christensen, Mette ;

Silahtaroglu, Asli ;

Bak, Mads ;

Heath, Catherine V. ;

Schwartz, Gary ;

Wells, Wendy ;

Kauppinen, Sakari ;

Cole, Charles N. .

CANCER RESEARCH, 2007, 67 (24) :11612-11620

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