Immunological determinants of disease caused by respiratory syncytial virus

被引：48

作者：

Graham, BS

机构：

[1] VANDERBILT UNIV,SCH MED,DEPT MED,NASHVILLE,TN 37232

[2] VANDERBILT UNIV,SCH MED,DEPT MICROBIOL & IMMUNOL,NASHVILLE,TN 37232

来源：

TRENDS IN MICROBIOLOGY | 1996年 / 4卷 / 07期

关键词：

D O I：

10.1016/0966-842X(96)10032-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Various disease syndromes caused by respiratory syncytial virus (RSV) may have a common mechanism of pathogenesis mediated by cytokines produced by type 2 T helper cells, The nature of the immune response to RSV is determined by the pattern of cytokines produced sequentially by many different cell types, Vaccination can influence the types of cytokine produced by selectively activating T cell subpopulations and inducing an immune response that clears the virus with minimal immunopathology.

引用

页码：290 / 294

页数：5

共 39 条

[1] ARNOLD R, 1994, IMMUNOLOGY, V82, P126
[2] BECKER S, 1991, J IMMUNOL, V147, P4307
[3] PARENTERAL ADMINISTRATION OF LIVE RESPIRATORY SYNCYTIAL VIRUS-VACCINE - RESULTS OF A FIELD TRIAL
BELSHE, RB
VANVORIS, LP
MUFSON, MA
[J]. JOURNAL OF INFECTIOUS DISEASES, 1982, 145 (03) : 311 - 319
[4] FIELD EVALUATION OF A RESPIRATORY SYNCYTIAL VIRUS VACCINE AND A TRIVALENT PARAINFLUENZA VIRUS VACCINE IN A PEDIATRIC POPULATION
CHIN, J
MAGOFFIN, RL
SHEARER, LA
SCHIEBLE, JH
LENNETTE, EH
[J]. AMERICAN JOURNAL OF EPIDEMIOLOGY, 1969, 89 (04) : 449 - +
[5] INTERFERON-PRODUCTION BY HUMAN MONONUCLEAR LEUKOCYTES - DIFFERENCES BETWEEN RESPIRATORY SYNCYTIAL VIRUS AND INFLUENZA-VIRUSES
CHONMAITREE, T
ROBERTS, NJ
DOUGLAS, RG
HALL, CB
SIMONS, RL
[J]. INFECTION AND IMMUNITY, 1981, 32 (01) : 300 - 303
[6] PRODUCTION OF INFECTIOUS HUMAN RESPIRATORY SYNCYTIAL VIRUS FROM CLONED CDNA CONFIRMS AN ESSENTIAL ROLE FOR THE TRANSCRIPTION ELONGATION-FACTOR FROM THE 5'-PROXIMAL OPEN READING FRAME OF THE M2 MESSENGER-RNA IN GENE-EXPRESSION AND PROVIDES A CAPABILITY FOR VACCINE DEVELOPMENT
COLLINS, PL
HILL, MG
CAMARGO, E
GROSFELD, H
CHANOCK, RM
MURPHY, BR
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (25) : 11563 - 11567
[7] CRONIN DC, 1995, J IMMUNOL, V154, P3118
[8] PURIFIED PROTEIN DERIVATIVE OF MYCOBACTERIUM-TUBERCULOSIS AND EXCRETORY-SECRETORY ANTIGEN(S) OF TOXOCARA-CANIS EXPAND INVITRO HUMAN T-CELLS WITH STABLE AND OPPOSITE (TYPE-1 T-HELPER OR TYPE-2 T-HELPER) PROFILE OF CYTOKINE PRODUCTION
DELPRETE, GF
DECARLI, M
MASTROMAURO, C
BIAGIOTTI, R
MACCHIA, D
FALAGIANI, P
RICCI, M
ROMAGNANI, S
[J]. JOURNAL OF CLINICAL INVESTIGATION, 1991, 88 (01) : 346 - 350
[9] ELIAS JA, 1994, J BIOL CHEM, V269, P22261
[10] DIFFERENTIAL PRODUCTION OF INTERFERON-GAMMA AND INTERLEUKIN-4 IN RESPONSE TO TH1-STIMULATING AND TH2-STIMULATING PATHOGENS BY GAMMA-DELTA T-CELLS IN-VIVO
FERRICK, DA
SCHRENZEL, MD
MULVANIA, T
HSIEH, B
FERLIN, WG
LEPPER, H
[J]. NATURE, 1995, 373 (6511) : 255 - 257

← 1 2 3 4 →