Smoking and autoimmune thyroid disease: the plot thickens

被引：38

作者：

Krassas, GE

Wiersinga, W

机构：

[1] Panagia Gen Hosp, Dept Diabet Endocrinol & Metab, Thessaloniki 54622, Greece

[2] Univ Amsterdam, Acad Med Ctr, Dept Endocrinol & Metab, NL-1012 WX Amsterdam, Netherlands

来源：

EUROPEAN JOURNAL OF ENDOCRINOLOGY | 2006年 / 154卷 / 06期

关键词：

D O I：

10.1530/eje.1.02157

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

New studies have shown that smoking may protect against the development of thyroid peroxidase antibodies, which may result in a decreased risk of Hashimoto's hypothyroidism (HH). whereas it stimulates the development of Graves hyperthyroidism (GH). According to the above-mentioned hypothesis, to stop smoking would decrease the risk of GH but increase the risk of HH. Also. smoking has been identified as one of the risk factors for the development or worsening of eye changes after I-131 treatment of GH. Additionally the outcome of medical treatment of Graves' ophthalmopathy (GO) is less favourable in smokers as compared to non-smokers. There is concern also about the effect of passive smoking on autoimmune thyroid disease. In a recent study it has been shown that the latter may have it deleterious effect on childhood GO.

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收藏

页码：777 / 780

页数：4

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