Oral treatment with Lactococcus lactis expressing Staphylococcus hyicus lipase enhances lipid digestion in pigs with induced pancreatic insufficiency

被引：51

作者：

Drouault, S

Juste, C

Marteau, P

Renault, P

Corthier, G

机构：

[1] INRA, Unite Ecol & Physiol Syst Digestif, F-78352 Jouy En Josas, France

[2] INRA, Unite Genet Microbienne, F-78352 Jouy En Josas, France

[3] Hop Pompidou, Gastroenterol Serv, F-75908 Paris, France

来源：

APPLIED AND ENVIRONMENTAL MICROBIOLOGY | 2002年 / 68卷 / 06期

关键词：

D O I：

10.1128/AEM.68.6.3166-3168.2002

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The Staphylococcus hyicus lip gene was cloned in Lactococcus lactis. Pancreatic insufficiency was induced by ligation of the pancreatic duct in pigs. In pigs who had undergone pancreatic ligation, the coefficient of fat absorption was higher after consumption of lipase-expressing L. lactis (91.9% +/- 3.7%) than that after consumption of the inactive control strain (78.4% +/- 2.4%).

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收藏

页码：3166 / 3168

页数：3

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