Intra-arterial steroid-injection therapy for steroid-refractory acute graft-versus-host disease with the evaluation of angiography

被引:11
作者
Nakai, K [1 ]
Tajima, K [1 ]
Tanigawa, N [1 ]
Matsumoto, N [1 ]
Zen, K [1 ]
Nomura, S [1 ]
Fujimoto, M [1 ]
Kishimoto, Y [1 ]
Amakawa, R [1 ]
Sawada, S [1 ]
Fukuhara, S [1 ]
机构
[1] Kansai Med Univ, Dept Internal Med 1, Moriguchi, Osaka 5708672, Japan
关键词
intra-arterial steroid-injection therapy; steroidrefractory; acute graft-versus-host disease; angiography;
D O I
10.1038/sj.bmt.1704523
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
We treated three patients with steroid-refractory acute graft-versus-host disease (aGVHD) with intra-arterial steroid-injection therapy (IAST). Two patients with gut aGVHD received IAST into both superior and inferior mesenteric arteries, while one patient with liver aGVHD received IAST into the proper hepatic artery. The volume of stools and the bilirubin level improved soon after IAST. Angiography of the superior and inferior mesenteric arteries was performed in the two patients with steroid-refractory gut aGVHD, and identical abnormal findings were obtained. IAST might be an earlier option for steroid-refractory aGVHD.
引用
收藏
页码:1231 / 1233
页数:3
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