SDS-subtilisin complex efficiently catalyzes synthesis of peptides in ethanol and 2-propanol

被引：14

作者：

Getun, IV ^{[1
]}

Filippova, IY ^{[1
]}

Lysogorskaya, EN ^{[1
]}

Oksenoit, ES ^{[1
]}

Anisimova, VV ^{[1
]}

Kolobanova, SV ^{[1
]}

Bacheva, AV ^{[1
]}

Stepanov, VM ^{[1
]}

机构：

[1] MOSCOW MV LOMONOSOV STATE UNIV,DEPT CHEM,MOSCOW 119899,RUSSIA

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1997年 / 7卷 / 20期

关键词：

D O I：

10.1016/S0960-894X(97)10058-0

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

An enzymatic synthesis of tripeptide Z-Ala-Ala-Leu-pNA, tetrapeptides Z-Ala-Ala-P-1-P-1'-Xaa, where P-1 = Leu, Trp, Met, Ala, Ile, Phe; P-1' = Phe, Ala, Leu; Xaa = pNA, NH2, pentapeptides Z-Ala-Ala-Leu-Ala-Ala-pNA and Z-Ala-Ala-Leu-Ala-Phe-pNA is described. The reactions were performed in organic solvents using SDS-subtilisin complex as a catalyst of the peptide bond synthesis. (C) 1997 Elsevier Science Ltd.

引用

页码：2691 / 2696

页数：6

共 7 条

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JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1997, 119 (01) :70-76

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