A new double-responsive block copolymer synthesized via RAFT polymerization:: Poly(N-isopropylacrylamide)-block-poly(acrylic acid)

被引：505

作者：

Schilli, CM

Zhang, MF

Rizzardo, E

Thang, SH

Chong, YK

Edwards, K

Karlsson, G

Müller, AHE

机构：

[1] Univ Bayreuth, D-95440 Bayreuth, Germany

[2] CSIRO Mol Sci, Clayton, Vic 3169, Australia

[3] Univ Uppsala, Dept Phys Chem, S-75123 Uppsala, Sweden

来源：

MACROMOLECULES | 2004年 / 37卷 / 21期

关键词：

D O I：

10.1021/ma035838w

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Poly(N-isopropylacrylamide)-block-poly(acrylic acid), PNIPAAm-b-PAA, with low polydispersity was prepared by reversible addition-fragmentation chain transfer (RAFT) polymerization in methanol. The block copolymers respond to both temperature and pH stimuli. The behaviour of the double-responsive block copolymers in solution was investigated by dynamic light scattering, temperature-sweep NMR, cryogenic transmission electron microscopy, and IR spectroscopy. The block copolymers form micelles in aqueous solutions in dependence of pH and temperature. Cloud point measurements indicated the formation of larger aggregates at pH 4.5 and temperatures above the lower critical solution temperature (LCST) of PNIPAAm. The solution behaviour is strongly influenced by hydrogen bonding interactions between the NIPAAm and acrylic acid blocks.

引用

页码：7861 / 7866

页数：6

共 13 条

[1] Switching the inside and the outside of aggregates of water-soluble block copolymers with double thermoresponsivity [J].