The microbiological hydroxylation of some 2,9-dioxygenated clovanes by Mucor plumbeus

被引：13

作者：

Arantes, SF ^{[1
]}

Hanson, JR ^{[1
]}

Mobbs, DJ ^{[1
]}

机构：

[1] Univ Sussex, Sch Chem Phys & Environm Sci, Brighton BN1 9QJ, E Sussex, England

来源：

PHYTOCHEMISTRY | 1999年 / 52卷 / 04期

基金：

英国工程与自然科学研究理事会;

关键词：

Mucor plumbeus; microbiological hydroxylation; sesquiterpenoids; clovanes;

D O I：

10.1016/S0031-9422(99)00257-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

The fungus, Mucor plumbeus, has been shown to hydroxylate 9 alpha- and 9 beta-hydroxy and 9-oxo-2 beta-methoxyclovane at C-6 and to reduce the 9-ketone stereospecifically to afford the 9 beta-alcohol. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：631 / 634

页数：4

共 8 条

[1]

REAKTIONEN MIT MIKROORGANISMEN .14. REDUKTION VON STEREOISOMEREN DEKALONEN-(1) UND EINIGEN VERWANDTEN BICYCLISCHEN UND TRICYCLISCHEN KETONEN DURCH CURVULARIA FALCATA [J].

ACKLIN, W ;

PRELOG, V ;

SCHENKER, F ;

SERDAREVIO, B ;

WALTER, P .

HELVETICA CHIMICA ACTA, 1965, 48 (07) :1725-+

[2]

AEBI M, 1953, J CHEM SOC, P3124

[3]

MICROBIOLOGICAL HYDROXYLATION OF STEROIDS .7. PATTERN OF DIHYDROXYLATION OF MONO-OXO-5 ALPHA-ANDROSTANES AND MONO-OXO-5 ALPHA-ESTRANES WITH FUNGUS RHISOPUS-NIGRICANS [J].

BROWNE, JW ;

DENNY, WA ;

JONES, ERH ;

MEAKINS, GD ;

MORISAWA, Y ;

PENDLEBURY, A ;

PRAGNELL, J .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1973, (14) :1493-1499

[4]

The cleavage of caryophyllene oxide catalysed by tetracyanoethylene [J].

Collado, IG ;

Hanson, JR ;

MaciasSanchez, AJ .

TETRAHEDRON, 1996, 52 (23) :7961-7972

[5]

Collado IG, 1998, NAT PROD REP, V15, P187

[6]

Fraga BM, 1998, NAT PROD REP, V15, P73

[7]

THE MECHANISM OF THE MICROBIAL HYDROXYLATION OF STEROIDS [J].

HOLLAND, HL .

CHEMICAL SOCIETY REVIEWS, 1982, 11 (04) :371-395

[8]

BIOCONVERSION OF SESQUITERPENES [J].

LAMARE, V ;

FURSTOSS, R .

TETRAHEDRON, 1990, 46 (12) :4109-4132

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