Contrast-Induced Nephropathy after Intravenous Administration: Fact or Fiction?

被引:95
作者
Katzberg, Richard W. [1 ]
Lamba, Ramit [1 ]
机构
[1] Univ Calif Davis, Med Ctr, Dept Radiol, Sacramento, CA 95819 USA
关键词
Contrast media; Kidney injury; Kidney function; CT; Acute renal failure; CHRONIC KIDNEY-DISEASE; ACUTE-RENAL-FAILURE; SERUM CREATININE; ENHANCED CT; MEDIA; RADIOCONTRAST; NEPHROTOXICITY; UROGRAPHY; RISK; PYELOGRAPHY;
D O I
10.1016/j.rcl.2009.06.002
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
100231 [临床病理学]; 100902 [航空航天医学];
摘要
Recent prospective clinical investigations in high-risk patients receiving intravenous contrast media for computed tomography (CT) suggest that the incidence and serious negative clinical outcomes are much less common than previously believed. Additional perspectives comparing random variations in serum creatinine in subjects not receiving contrast media show similar fluctuations that would equate to contrast-induced nephrotoxicity (CIN). Putative mechanisms for how CIN could cause death or other serious adverse clinical consequences have not been elucidated.
引用
收藏
页码:789 / +
页数:13
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