Characteristics of Enzyme-Based ZnO/Zn0.7Mg0.3O Heterojunction Field-Effect Transistor as Glucose Sensor

被引：16

作者：

Koike, Kazuto ^{[1
]}

Takagi, Daisuke ^{[1
]}

Hashimoto, Mitsuhiro ^{[1
]}

Hashimoto, Takahito ^{[1
]}

Inoue, Tomoyuki ^{[1
]}

Ogata, Ken-ichi ^{[1
]}

Sasa, Shigehiko ^{[1
]}

Inoue, Masataka ^{[1
]}

Yano, Mitsuaki ^{[1
]}

机构：

[1] Osaka Inst Technol, Nanomat Microdevices Res Ctr, Asahi Ku, Osaka 5358585, Japan

来源：

JAPANESE JOURNAL OF APPLIED PHYSICS | 2009年 / 48卷 / 04期

关键词：

MONOLAYER; OXIDASE;

D O I：

10.1143/JJAP.48.04C081

中图分类号：

O59 [应用物理学];

学科分类号：

摘要：

The characteristics of an enzyme-based ZnO/Zn0.7Mg0.3O heterojunction field-effect transistor (HFET) for glucose sensing are reported. The enzyme glucose oxidase (GOD) was immobilized on an amine-modified gate electrode of the ZnO/Zn0.7Mg0.3O HIFET, and glucose sensing was performed by detecting biocatalytically yielded protons using an ion-sensitive function of the gate electrode. The chemical bonding states of the amine-modified and GOD-immobilized surfaces were analyzed by X-ray photoemission spectroscopy, and the enzyme activity of GOD was examined by a colorimetric method. In agreement with the promising results of these experiments, this enzyme-based HFET exhibited stable sensing performance with a linear response in a wide range of glucose concentrations from 0 to 4 mg-cm(-3) and at a short time constant less than 20s. (c) 2009 The Japan Society of Applied Physics

引用

页数：4

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