Molecular and functional aspects of anionic channels activated during regulatory volume decrease in mammalian cells

被引：98

作者：

Fürst, J

Gschwentner, M

Ritter, M

Bottà, G

Jakab, M

Mayer, M

Garavaglia, L

Bazzini, C

Rodighiero, S

Meyer, G

Eichmüller, S

Wöll, E

Paulmichl, M

机构：

[1] Univ Innsbruck, Inst Physiol, A-6020 Innsbruck, Austria

[2] Univ Milan, Dept Physiol & Biochem, I-20133 Milan, Italy

[3] Univ Innsbruck, Dept Internal Med, A-6020 Innsbruck, Austria

来源：

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY | 2002年 / 444卷 / 1-2期

关键词：

RVD; VSOAC; VRAC; I-Cl; I-vol; I-swell; ORCC; RVDC; swelling;

D O I：

10.1007/s00424-002-0805-1

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

The ability of cells to readjust their volume after swelling, a phenomenon known as regulatory volume decrease (RVD), is a fundamental biological achievement guaranteeing survival and function of cells under osmotic stress. This article reviews the mechanisms of RVD in mammalian cells with special emphasis on the activation of ion channels during RVD.

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页码：1 / 25

页数：25

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