Structural basis of allosteric changes in the GroEL mutant Arg197->Ala

被引：50

作者：

White, HE

Chen, SX

Roseman, AM

Yifrach, O

Horovitz, A

Saibil, HR

机构：

[1] UNIV LONDON BIRKBECK COLL,DEPT CRYSTALLOG,LONDON WC1E 7HX,ENGLAND

[2] WEIZMANN INST SCI,DEPT BIOL STRUCT,IL-76100 REHOVOT,ISRAEL

来源：

NATURE STRUCTURAL BIOLOGY | 1997年 / 4卷 / 09期

关键词：

D O I：

10.1038/nsb0997-690

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Combined kinetic and cryo-EM analysis of the R197A mutant of GroEL provides insight into the allosteric switching of GroEL, which is at the heart of the chaperonin mechanism.

引用

页码：690 / 694

页数：5

共 34 条

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