Expression and localization of the Na-K-2Cl cotransporter in the rat cochlea

被引：25

作者：

Goto, S ^{[1
]}

Oshima, T ^{[1
]}

Ikeda, K ^{[1
]}

Ueda, N ^{[1
]}

Takasaka, T ^{[1
]}

机构：

[1] TOHOKU UNIV,SCH MED,DEPT OTORHINOLARYNGOL,AOBA KU,SENDAI,MIYAGI 98077,JAPAN

来源：

BRAIN RESEARCH | 1997年 / 765卷 / 02期

关键词：

stria vascularis; marginal cell; fibrocyte; spiral ligament; bumetanide-sensitive Na-K-2Cl cotransporter;

D O I：

10.1016/S0006-8993(97)00679-3

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

We identified the localization of the basolateral bumetanide-sensitive Na-K-2Cl cotransporter (BSC2) in the cochlea using an in situ hybridization method. In the rat cochlea, the BSC2 mRNA was mainly expressed in the strial marginal cells. Although the fibrocytes localized at the spiral prominence showed a weak expression of BSC2 mRNA, no expression was observed in the organ of Corti or spiral ganglion cells. The present findings are well consistent with a proposed cell model of ion transport in the marginal cell. (C) 1997 Elsevier Science B.V.

引用

页码：324 / 326

页数：3

共 19 条

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