Protean behavior by agonists: agonist-directed trafficking of receptor signaling

被引：7

作者：

Brink, CB ^{[1
]}

机构：

[1] Potchefstroom Univ Christian Higher Educ, Div Pharmacol, ZA-2520 Potchefstroom, South Africa

来源：

TRENDS IN PHARMACOLOGICAL SCIENCES | 2002年 / 23卷 / 10期

关键词：

D O I：

10.1016/S0165-6147(02)02079-5

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：454 / 455

页数：2

共 10 条

[1] Effector pathway-dependent relative efficacy at serotonin type 2A and 2C receptors: Evidence for agonist-directed trafficking of receptor stimulus [J].

Berg, KA ;

Maayani, S ;

Goldfarb, J ;

Scaramellini, C ;

Leff, P ;

Clarke, WP .

MOLECULAR PHARMACOLOGY, 1998, 54 (01) :94-104

[2]

Brink CB, 2000, J PHARMACOL EXP THER, V294, P539

[3]

Chidiac P, 2002, METHOD ENZYMOL, V343, P3

[4] AGONIST-RECEPTOR EFFICACY .2. AGONIST TRAFFICKING OF RECEPTOR SIGNALS [J].

KENAKIN, T .

TRENDS IN PHARMACOLOGICAL SCIENCES, 1995, 16 (07) :232-238

[5] PHARMACOLOGICAL PROTEUS [J].

KENAKIN, T .

TRENDS IN PHARMACOLOGICAL SCIENCES, 1995, 16 (08) :256-258

[6] Inverse, protean, and ligand-selective agonism: matters of receptor conformation [J].

Kenakin, T .

FASEB JOURNAL, 2001, 15 (03) :598-611

[7]

LANG G, 1999, MOL PHARMACOL, V56, P651

[8] A three-state receptor model of agonist action [J].

Leff, P ;

Scaramellini, C ;

Law, C ;

McKechnie, K .

TRENDS IN PHARMACOLOGICAL SCIENCES, 1997, 18 (10) :355-362

[9] Evidence for protean agonism of RX 831003 at α2A-adrenoceptors by co-expression with different Gα protein subunits [J].

Pauwels, PJ ;

Rauly, I ;

Wurch, T ;

Colpaert, FC .

NEUROPHARMACOLOGY, 2002, 42 (06) :855-863

[10]

Scaramellini C, 2002, METHOD ENZYMOL, V343, P17

← 1 →