Pulsatilla saponin D:: the antitumor principle from Pulsatilla koreana

被引：80

作者：

Kim, Y ^{[1
]}

Bang, SC ^{[1
]}

Lee, JH ^{[1
]}

Ahn, BZ ^{[1
]}

机构：

[1] SP Pharmaceut Co Ltd, Kong Ju 314923, Chungnam, South Korea

来源：

ARCHIVES OF PHARMACAL RESEARCH | 2004年 / 27卷 / 09期

关键词：

Pulsatilla saponin D; antitumor activity;

D O I：

10.1007/BF02975843

中图分类号：

R914 [药物化学];

学科分类号：

100701 [药物化学];

摘要：

By bioassay-guided separation, an already known saponin, Pulsatilla saponin D was isolated from the root of Pulsatilla koreana Nakai as a antitumor component when evaluated by in vivo antitumor activity as well as in vitro cytotoxic activity test. It showed potent inhibition rate of tumor growth (IR, 82 %) at the dose of 6.4 mg/kg on the BIDF1 mice bearing LLC cells.

引用

页码：915 / 918

页数：4

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