JAK2V617F mutation can occur exclusively in the erythroid lineage and be absent in granulocytes and progenitor cells in classic myeloproliferative disorders

被引:9
作者
Zehentner, Barbara K. [1 ]
Loken, Michael R. [1 ]
Wells, Denise A. [1 ]
机构
[1] Hematol Inc, Seattle, WA USA
关键词
D O I
10.1002/ajh.20663
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:806 / 807
页数:2
相关论文
共 5 条
[1]   Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders [J].
Baxter, EJ ;
Scott, LM ;
Campbell, PJ ;
East, C ;
Fourouclas, N ;
Swanton, S ;
Vassiliou, GS ;
Bench, AJ ;
Boyd, EM ;
Curtin, N ;
Scott, MA ;
Erber, WN ;
Green, AR .
LANCET, 2005, 365 (9464) :1054-1061
[2]   The Jak2V617F mutation, PRV-1 overexpression, and EEC formation define a similar cohort of MPD patients [J].
Goerttler, PS ;
Steimle, C ;
März, E ;
Johansson, PL ;
Andreasson, B ;
Griesshammer, M ;
Gisslinger, H ;
Heimpel, H ;
Pahl, HL .
BLOOD, 2005, 106 (08) :2862-2864
[3]   A gain-of-function mutation of JAK2 in myeloproliferative disorders [J].
Kralovics, R ;
Passamonti, F ;
Buser, AS ;
Teo, S ;
Tiedt, R ;
Passweg, JR ;
Tichelli, A ;
Cazzola, M ;
Skoda, RC .
NEW ENGLAND JOURNAL OF MEDICINE, 2005, 352 (17) :1779-1790
[4]   Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis [J].
Levine, RL ;
Wadleigh, M ;
Cools, J ;
Ebert, BL ;
Wernig, G ;
Huntly, BJP ;
Boggon, TJ ;
Wlodarska, L ;
Clark, JJ ;
Moore, S ;
Adelsperger, J ;
Koo, S ;
Lee, JC ;
Gabriel, S ;
Mercher, T ;
D'Andrea, A ;
Fröhling, S ;
Döhner, K ;
Marynen, P ;
Vandenberghe, P ;
Mesa, RA ;
Tefferi, A ;
Griffin, JD ;
Eck, MJ ;
Sellers, WR ;
Meyerson, M ;
Golub, TR ;
Lee, SJ ;
Gilliland, DG .
CANCER CELL, 2005, 7 (04) :387-397
[5]   The JAK2V617F tyrosine kinase mutation in myelofibrosis with myeloid metaplasia:: lineage specificity and clinical correlates [J].
Tefferi, A ;
Lasho, TL ;
Schwager, SM ;
Steensma, DP ;
Mesa, RA ;
Li, CY ;
Wadleigh, M ;
Gilliland, DG .
BRITISH JOURNAL OF HAEMATOLOGY, 2005, 131 (03) :320-328