Treatment of superficial cutaneous vascular lesions: experience with the KTP 532 nm laser

被引:62
作者
Clark, C [1 ]
Cameron, H [1 ]
Moseley, H [1 ]
Ferguson, J [1 ]
Ibbotson, SH [1 ]
机构
[1] Univ Dundee, Ninewells Hosp Med Sch, Dept Dermatol, Photobiol Unit, Dundee DD1 9SY, Scotland
关键词
KTP 532 nm laser; spider angioma; superficial vascular lesions; telangiectasia;
D O I
10.1007/s10103-004-0294-x
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Whilst most facial telangiectasias respond well to short-pulse-duration pulsed dye laser therapy, studies have shown that for the treatment of larger vessels these short-duration pulses are sub-optimal. Long-pulse frequency-doubled neodymium:YAG lasers have been introduced with pulse durations ranging from 1-50 ms and treatment beam diameters of up to 4 mm. We report the results of KTP/532 nm laser treatment for superficial vascular skin lesions. The aim was to determine the efficacy of the KTP/532 nm laser in the treatment of superficial cutaneous vascular lesions at a regional dermatology centre in a 2 year retrospective analysis. Patients were referred from general dermatology clinics to a purpose-built laser facility. A test dose was performed at the initial consultation and thereafter patients were reviewed and treated at 6 week intervals. Outcome was graded into five classifications by the patient and operator independently based on photographic records: clear, marked improvement, partial response, poor response, and no change or worsening. Over the 2 year period, 204 patients with 246 diagnoses were treated [156 female; median age 41 (range 1-74) years; Fitzpatrick skin types I-III]. Equal numbers of spider angioma (102) and facial telangiectasia (102) were treated. Of those patients who completed treatment and follow up, 57/58 (98%) of spider angiomas and 44/49 (90%) of facial telangiectasia markedly improved or cleared. Satisfactory treatment outcomes, with one clearance and two partial responses, occurred in three of five patients with port-wine stain. Few patients experienced adverse effects: two declined further treatment due to pain, and a small area of minimal superficial scarring developed in one case. Two patients developed mild persistent post-inflammatory hyperpigmentation, and one subject experienced an episode of acute facial erythema, swelling and blistering after one treatment. The KTP/532 nm frequency-doubled neodymium:YAG laser is a safe and effective treatment for common superficial cutaneous vascular lesions in patients with Fitzpatrick skin types I-III.
引用
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页码:1 / 5
页数:5
相关论文
共 16 条
[1]   Long pulse 532-nm laser treatment of facial telangiectasia [J].
Adrian, RM ;
Tanghetti, EA .
DERMATOLOGIC SURGERY, 1998, 24 (01) :71-74
[2]   SELECTIVE PHOTOTHERMOLYSIS - PRECISE MICROSURGERY BY SELECTIVE ABSORPTION OF PULSED RADIATION [J].
ANDERSON, RR ;
PARRISH, JA .
SCIENCE, 1983, 220 (4596) :524-527
[3]   THE OPTICS OF HUMAN-SKIN [J].
ANDERSON, RR ;
PARRISH, JA .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1981, 77 (01) :13-19
[4]   Potassium titanyl phosphate laser treatment of resistant port-wine stains [J].
Chowdhury, MMU ;
Harris, S ;
Lanigan, SW .
BRITISH JOURNAL OF DERMATOLOGY, 2001, 144 (04) :814-817
[5]   THERMAL RELAXATION OF PORT-WINE STAIN VESSELS PROBED IN-VIVO - THE NEED FOR 1-10 MILLISECOND LASER-PULSE TREATMENT [J].
DIERICKX, CC ;
CASPARIAN, JM ;
VENUGOPALAN, V ;
FARINELLI, WA ;
ANDERSON, RR .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1995, 105 (05) :709-714
[6]   EFFECT OF DYE-LASER PULSE DURATION ON SELECTIVE CUTANEOUS VASCULAR INJURY [J].
GARDEN, JM ;
TAN, OT ;
KERSCHMANN, R ;
BOLL, J ;
FURUMOTO, H ;
ANDERSON, RR ;
PARRISH, JA .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1986, 87 (05) :653-657
[7]   A prospective study of the impact of laser treatment on vascular lesions [J].
Gupta, G ;
Bilsland, D .
BRITISH JOURNAL OF DERMATOLOGY, 2000, 143 (02) :356-359
[8]  
Katugampola GA, 1997, BRIT J DERMATOL, V137, P750
[9]   Update on the clinical management of port wine stains [J].
Kelly, KM ;
Nelson, JS .
LASERS IN MEDICAL SCIENCE, 2000, 15 (04) :220-226
[10]  
Lanigan S.W., 2000, LASERS DERMATOLOGY