Dielectrophoresis for Biomedical Sciences Applications: A Review

被引:179
作者
Abd Rahman, Nurhaslina [1 ,2 ]
Ibrahim, Fatimah [1 ,2 ]
Yafouz, Bashar [1 ,2 ,3 ]
机构
[1] Univ Malaya, Dept Biomed Engn, Fac Engn, Kuala Lumpur 50603, Malaysia
[2] Univ Malaya, CIME, Fac Engn, Kuala Lumpur 50603, Malaysia
[3] Taiz Univ, Fac Engn & Informat Technol, Taizi 6803, Yemen
关键词
dielectrophoresis; biomedical sciences; diagnostic; point-of-care; EMBRYONIC STEM-CELLS; RT-PCR ASSAY; CANCER-CELLS; DRUG DISCOVERY; DIELECTRIC-PROPERTIES; PHYSIOLOGICAL MEDIA; ADIPOSE-TISSUE; NUCLEIC-ACIDS; TUMOR-CELLS; BLOOD-CELLS;
D O I
10.3390/s17030449
中图分类号
O65 [分析化学];
学科分类号
070302 [分析化学];
摘要
Dielectrophoresis (DEP) is a label-free, accurate, fast, low-cost diagnostic technique that uses the principles of polarization and the motion of bioparticles in applied electric fields. This technique has been proven to be beneficial in various fields, including environmental research, polymer research, biosensors, microfluidics, medicine and diagnostics. Biomedical science research is one of the major research areas that could potentially benefit from DEP technology for diverse applications. Nevertheless, many medical science research investigations have yet to benefit from the possibilities offered by DEP. This paper critically reviews the fundamentals, recent progress, current challenges, future directions and potential applications of research investigations in the medical sciences utilizing DEP technique. This review will also act as a guide and reference for medical researchers and scientists to explore and utilize the DEP technique in their research fields.
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页数:27
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