Erythrocyte magnesium concentration as an index of magnesium status: a perspective from a magnesium supplementation study

被引：26

作者：

Basso, LE ^{[1
]}

Ubbink, JB ^{[1
]}

Delport, R ^{[1
]}

机构：

[1] Univ Pretoria, Dept Chem Pathol, ZA-0001 Pretoria, South Africa

来源：

CLINICA CHIMICA ACTA | 2000年 / 291卷 / 01期

关键词：

erythrocyte; plasma; magnesium; analytical variation; biological variation; critical difference;

D O I：

10.1016/S0009-8981(99)00168-0

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

We investigated the utility of erythrocyte magnesium concentrations as an index of magnesium status. Calculated from the analytical and biological variation, the critical difference, i.e. the difference between results from serial specimens before they can be said to be statistically different, was 22.4% (P < 0.05). Magnesium supplementation of 250 mg/day for 3 weeks in 20 women with an erythrocyte magnesium concentration less than the 15th percentile of a population sample (n = 219), resulted in an increase in erythrocyte magnesium concentration of only 1.6%. We therefore conclude that sequential erythrocyte magnesium measurements are not useful for the monitoring of individual changes in magnesium intake and status, (C) 2000 Elsevier Science B.V. All rights reserved.

引用

页码：1 / 8

页数：8

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