What's special about secretory lysosomes?

被引：24

作者：

Griffiths, G ^{[1
]}

机构：

[1] Univ Oxford, Sir William Dunn Sch Pathol, Oxford OX1 3RE, England

来源：

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY | 2002年 / 13卷 / 04期

关键词：

secretory lysosomes; immune system; CTL;

D O I：

10.1016/S1084-9521(02)00057-5

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Lysosomes are organelles specialised for their role in intracellular protein degradation. A small number of cell types also use their lysosomes as regulated secretory organelles. These secretory lysosomes package additional secretory products, respond to extracellular stimuli and fuse with the plasma membrane to release their contents. Recent research has identified unique components of the secretary machinery in these cells. However, studies on conventional lysosomes in non-secretory cells reveal that even their lysosomes can fuse with the plasma membrane in response to membrane damage. Mat then is special about secretary lysosomes?

引用

页码：279 / 284

页数：6

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