General One-Pot Method for the Preparation of N-tert-Butanesulfinylamine Diastereomer Mixtures as Standards for Stereoselectivity Determinations

被引：19

作者：

Brak, Katrien ^{[1
]}

Barrett, Kimberly T. ^{[1
]}

Ellman, Jonathan A. ^{[1
]}

机构：

[1] Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2009年 / 74卷 / 09期

关键词：

ASYMMETRIC-SYNTHESIS; ARYLBORONIC ACIDS; AMINES; IMINES; ALDIMINES; ADDITIONS; REAGENTS; ESTERS;

D O I：

10.1021/jo900353p

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The one-pot preparation of N-sulfinylamine diastereomers proceeds in excellent yields (84-98%) for a diverse set of N-sulfinyl imine addition products. The method is operationally simple and extractive isolation provides analytically pure mixtures of diastereomers as standards for the rapid and accurate determination of N-sulfinylamine diastereomeric purity.

引用

页码：3606 / 3608

页数：3

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