Activity of glycylcyclines CL 329998 and CL 331002 against minocycline-resistant and other strains of methicillin-resistant Staphylococcus aureus

被引：9

作者：

HamiltonMiller, JMT

Shah, S

机构：

[1] Department of Medical Microbiology, Roy. Free Hosp. School of Medicine

来源：

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 1996年 / 37卷 / 06期

关键词：

D O I：

10.1093/jac/37.6.1171

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Two glycylcyclines have been tested against 191 strains of methicillin-resistant Staphylococcus aureus, 72 of which were resistant to minocycline, isolated from many parts of the world. MICs of CL 329998 ranged from 0.06 to 4 mg/L, with MIC(50) and MIC(50) 0.5 and 2 mg/L, respectively. CL 331002 was slightly less potent, having an MIC range 0.12-16 mg/L and MIC(50) and MIC(90) values of 1 and 4 mg/L, respectively.

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页码：1171 / 1175

页数：5

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