Virion-associated protein kinases

被引：18

作者：

Hui, EKW ^{[1
]}

机构：

[1] Univ Calif Los Angeles, Sch Med, Dept Microbiol Mol Genet & Immunol, Los Angeles, CA 90034 USA

来源：

CELLULAR AND MOLECULAR LIFE SCIENCES | 2002年 / 59卷 / 06期

关键词：

virion-associated protein kinase; protein kinase; virus;

D O I：

10.1007/s00018-002-8479-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Many purified virions, particularly enveloped virus particles (such as retrovirus, hepadnavirus, herpesvirus, orthomyxovirus, and paramyxovirus), contain protein kinase (PK) activity. This type of PK has been called virion-associated protein kinase (VAPK). Even though some VAPKs are identified either as a cellular PK or viral-encoded kinase, many remain to be identified. Although the roles of VAPKs are not yet well characterized, there is ample evidence to suggest their importance in viral infectivity, uncoating, transcription, and replication.

引用

页码：920 / 931

页数：12

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