Population biology of emerging and re-emerging pathogens

被引:214
作者
Woolhouse, MEJ [1 ]
机构
[1] Univ Edinburgh, Coll Med & Vet Med, Ctr Infect Dis, Roslin EH25 9RG, Midlothian, Scotland
基金
英国惠康基金;
关键词
D O I
10.1016/S0966-842X(02)02428-9
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Emerging and re-emerging pathogens present a huge challenge to human and veterinary medicine. Emergence is most commonly associated with ecological change, and specific risk factors are related to the type of pathogen, route of transmission and host range. The biological determinants of host range remain poorly understood but most pathogens can infect multiple hosts, and three-quarters of emerging human pathogens are zoonotic. Surveillance is a key defence against emerging pathogens but will often need to be integrated across human, domestic animal and wildlife populations.
引用
收藏
页码:S3 / S7
页数:5
相关论文
共 17 条
  • [1] ANDERSON R M, 1991
  • [2] Transmission dynamics and epidemiology of BSE in British cattle
    Anderson, RM
    Donnelly, CA
    Ferguson, NM
    Woolhouse, MEJ
    Watt, CJ
    Udy, HJ
    MaWhinney, S
    Dunstan, SP
    Southwood, TRE
    Wilesmith, JW
    Ryan, JBM
    Hoinville, LJ
    Hillerton, JE
    Austin, AR
    Wells, GAH
    [J]. NATURE, 1996, 382 (6594) : 779 - 788
  • [3] [Anonymous], 2000, World Health Report 2000: Health Systems: Improving Performance
  • [4] Diseases of humans and their domestic mammals: pathogen characteristics, host range and the risk of emergence
    Cleaveland, S
    Laurenson, MK
    Taylor, LH
    [J]. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 2001, 356 (1411) : 991 - 999
  • [5] Wildlife ecology - Emerging infectious diseases of wildlife - Threats to biodiversity and human health
    Daszak, P
    Cunningham, AA
    Hyatt, AD
    [J]. SCIENCE, 2000, 287 (5452) : 443 - 449
  • [6] Emerging infectious pathogens of wildlife
    Dobson, A
    Foufopoulos, J
    [J]. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 2001, 356 (1411) : 1001 - 1012
  • [7] Monitoring and surveillance for rare health-related events:: a review from the veterinary perspective
    Doherr, MG
    Audigé, L
    [J]. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 2001, 356 (1411) : 1097 - 1106
  • [8] Descriptive epidemiology of the 2001 foot-and-mouth disease epidemic in Great Britain: the first five months
    Gibbens, JC
    Sharpe, CE
    Wilesmith, JW
    Mansley, LM
    Michalopoulou, E
    Ryan, JBM
    Hudson, M
    [J]. VETERINARY RECORD, 2001, 149 (24) : 729 - +
  • [9] Isolation of enterohemorrhagic Escherichia coli O157 strains from patients with hemolytic-uremic syndrome by using immunomagnetic separation, DNA-based methods, and direct culture
    Karch, H
    JanetzkiMittmann, C
    Aleksic, S
    Datz, M
    [J]. JOURNAL OF CLINICAL MICROBIOLOGY, 1996, 34 (03) : 516 - 519
  • [10] Contribution to the mathematical theory of epidemics
    Kermack, WO
    McKendrick, AG
    [J]. PROCEEDINGS OF THE ROYAL SOCIETY OF LONDON SERIES A-CONTAINING PAPERS OF A MATHEMATICAL AND PHYSICAL CHARACTER, 1927, 115 (772) : 700 - 721