Competition and compensation: Coupled to death in development and cancer

被引：60

作者：

Abrams, JM ^{[1
]}

机构：

[1] Univ Texas, SW Med Ctr, Dept Cell Biol, Dallas, TX 75390 USA

来源：

CELL | 2002年 / 110卷 / 04期

关键词：

D O I：

10.1016/S0092-8674(02)00904-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Developing systems exhibit robust and tolerant properties in the form of compensation and competition within cell groups. Fundamentally, these behaviors are governed by mechanisms that elicit proliferation and apoptosis. Recent insights from the Drosophila system implicate new determinants that specify "winners" and "losers" in this process.

引用

页码：403 / 406

页数：4

共 19 条

[1] An emerging blueprint for apoptosis in Drosophila
Abrams, JM
[J]. TRENDS IN CELL BIOLOGY, 1999, 9 (11) : 435 - 440
[2] Distortion of proximodistal information causes JNK-dependent apoptosis in Drosophila wing
Adachi-Yamada, T
Fujimura-Kamada, K
Nishida, Y
Matsumoto, K
[J]. NATURE, 1999, 400 (6740) : 166 - 169
[3] Error and attack tolerance of complex networks
Albert, R
Jeong, H
Barabási, AL
[J]. NATURE, 2000, 406 (6794) : 378 - 382
[4] The molecular basis and potential role of survivin in cancer diagnosis and therapy
Altieri, DC
[J]. TRENDS IN MOLECULAR MEDICINE, 2001, 7 (12) : 542 - 547
[5] Burke R, 1996, DEVELOPMENT, V122, P2261
[6] Proliferation, cell cycle and apoptosis in cancer
Evan, GI
Vousden, KH
[J]. NATURE, 2001, 411 (6835) : 342 - 348
[7] GARCIABELLIDO A, 1975, CIBA F SYMP, P161, DOI DOI 10.1002/9780470720110.CH8
[8] A matter of life and death
Green, DR
Evan, GI
[J]. CANCER CELL, 2002, 1 (01) : 19 - 30
[9] The Drosophila Hox gene Deformed sculpts head morphology via direct regulation of the apoptosis activator reaper
Lohmann, I
McGinnis, N
Bodmer, M
McGinnis, W
[J]. CELL, 2002, 110 (04) : 457 - 466
[10] Destabilizing influences in apoptosis: sowing the seeds of IAP destruction
Martin, SJ
[J]. CELL, 2002, 109 (07) : 793 - 796

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