Tiny dancers: the integrin-growth factor nexus in angiogenic signaling

被引：41

作者：

Smyth, SS

Patterson, C

机构：

[1] Univ N Carolina, Carolina Cardiovasc Biol Ctr, Chapel Hill, NC 27599 USA

[2] Univ N Carolina, Dept Med Cardiol, Chapel Hill, NC 27599 USA

[3] Univ N Carolina, Dept Cell & Dev Biol, Chapel Hill, NC 27599 USA

[4] Univ N Carolina, Dept Pharmacol, Chapel Hill, NC 27599 USA

来源：

JOURNAL OF CELL BIOLOGY | 2002年 / 158卷 / 01期

关键词：

angiogenesis; growth factors; growth factor receptors; integrins; signal transduction pathways;

D O I：

10.1083/jcb.200202100

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

A vital step in growth factor-driven angiogenesis is the coordinated engagement of endothelial integrins with the extracellular matrix. The molecular mechanisms that partner growth factors and integrins are being elucidated, revealing an intricate interaction of surface receptors and their signaling pathways.

引用

收藏

页码：17 / 21

页数：5

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