Cesarean scar pregnancies successfully treated with methotrexate

被引:16
作者
Muraji, Miho [1 ]
Mabuchi, Seiji [1 ]
Hisamoto, Koji [2 ]
Muranishi, Mariko [2 ]
Kanagawa, Takeshi [1 ]
Nishio, Yukihiro [2 ]
Kimura, Tadashi [1 ]
机构
[1] Osaka Univ, Dept Obstet & Gynecol, Grad Sch Med, Suita, Osaka 5650871, Japan
[2] Osaka Police Hosp, Dept Obstet & Gynecol, Tennoji Ku, Suita, Osaka 5650871, Japan
关键词
Cesarean scar pregnancy; methotrexate; ultrasonography; ECTOPIC PREGNANCY; SECTION SCAR; MANAGEMENT; DIAGNOSIS;
D O I
10.1080/00016340902883141
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Three cases of cesarean scar pregnancy successfully treated with methotrexate are described. The diagnosis was confirmed by transvaginal sonographic examinations showing a well-formed gestational sac in the myometrium of the lower uterine segment. Initial treatment with a systemic injection of 50 mg of methotrexate was not sufficient, and multiple doses were required to obtain a complete remission in two cases. In a case with a beta-hCG level of more than 20,000 mIU/mL with a viable embryo in a gestational sac, a combination of systemic and local treatment with methotrexate was required. It took 7-11 weeks for the beta-hCG level to become undetectable and 12-17 weeks for the cesarean scar pregnancy mass to disappear completely.
引用
收藏
页码:720 / 723
页数:4
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