Comparison of immunofluorescence, Western blotting, and cross-adsorption assays for diagnosis of African tick bite fever

被引：23

作者：

Jensenius, M

Fournier, PE

Vene, S

Ringertz, SH

Myrvang, B

Raoult, D

机构：

[1] Aker Univ Hosp, Dept Internal Med, NO-0514 Oslo, Norway

[2] Aker Univ Hosp, Dept Bacteriol, NO-0514 Oslo, Norway

[3] Ullevaal Univ Hosp, Dept Infect Dis, Oslo, Norway

[4] Univ Mediterrannee, Unit Rickettsies, Marseille, France

[5] Swedish Inst Infect Dis Control, Solna, Sweden

来源：

CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY | 2004年 / 11卷 / 04期

关键词：

D O I：

10.1128/CDLI.11.4.786-788.2004

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In testing paired serum samples from 40 consecutive cases of African tick bite fever, we detected diagnostic antibodies against spotted fever group rickettsiae in 45% of the patients by immunofluorescence assay (IFA) and in 100% of the patients by Western blotting (WB) (P < 0.01). A specific diagnosis of Rickettsia africae infection could be established in 15% of the patients by IFA and in 73% of the patients by a combination of WB and cross-adsorption assays (P < 0.01).

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页码：786 / 788

页数：3

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