Interactions between enteropathogenic Escherichia coli and host epithelial cells

被引：199

作者：

Donnenberg, MS

Kaper, JB

Finlay, BB

机构：

[1] UNIV MARYLAND,SCH MED,DEPT MED,CTR VACCINE DEV,BALTIMORE,MD 21201

[2] UNIV BRITISH COLUMBIA,BIOTECHNOL LAB,VANCOUVER,BC V6T 1Z3,CANADA

[3] UNIV BRITISH COLUMBIA,DEPT BIOCHEM & MOL BIOL,VANCOUVER,BC V6T 1Z3,CANADA

[4] UNIV BRITISH COLUMBIA,DEPT IMMUNOL & MICROBIOL,VANCOUVER,BC V6T 1Z3,CANADA

来源：

TRENDS IN MICROBIOLOGY | 1997年 / 5卷 / 03期

关键词：

D O I：

10.1016/S0966-842X(97)01000-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The pathogenesis of enteropathogenic Escherichia coli (EPEC) infection is emerging as a paradigm for a multistage microorganism-host cell interaction. Both type IV fimbriae and a type III secretion apparatus play principal roles in interactions between the bacteria and host cells. Recent data suggest that bacteria-induced signal transduction activates the receptor that allows tenacious adherence of the bacteria to the host cell surface.

引用

页码：109 / 114

页数：6

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