Pain assessment in animal models of osteoarthritis

被引：110

作者：

Piel, Margaret J. ^{[1
]}

Kroin, Jeffrey S. ^{[2
]}

van Wijnen, Andre J. ^{[6
]}

Kc, Ranjan ^{[3
]}

Im, Hee-Jeong ^{[3
,4
,5
]}

机构：

[1] Comparat Med Consultants, Chicago, IL 60631 USA

[2] Rush Univ, Med Ctr, Dept Anesthesiol, Chicago, IL 60612 USA

[3] Rush Univ, Med Ctr, Dept Biochem, Chicago, IL 60612 USA

[4] Rush Univ, Med Ctr, Dept Orthoped Surg, Chicago, IL 60612 USA

[5] Rush Univ, Med Ctr, Dept Internal Med, Rheumatol Sect, Chicago, IL 60612 USA

[6] Mayo Clin, Dept Orthoped Surg & & Mol Biol, Rochester, MN 55905 USA

来源：

GENE | 2014年 / 537卷 / 02期

基金：

美国国家卫生研究院;

关键词：

Rodents; Dogs; Horses; Rabbits; Guinea pigs; RAT; ALLODYNIA;

D O I：

10.1016/j.gene.2013.11.091

中图分类号：

Q3 [遗传学];

学科分类号：

071007 [遗传学];

摘要：

Assessment of pain in animal models of osteoarthritis is integral to interpretation of a model's utility in representing the clinical condition, and enabling accurate translational medicine. Here we describe behavioral pain assessments available for small and large experimental osteoarthritic pain animal models. (C) 2013 Elsevier B.V. All rights reserved.

引用

收藏

页码：184 / 188

页数：5

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