Intramolecular Diels-Alder and tandem intramolecular Diels-Alder/1,3-dipolar cycloaddition reactions of 1,3,4-oxadiazoles

被引：108

作者：

Wilkie, GD

Elliott, GI

Blagg, BSJ

Wolkenberg, SE

Soenen, DR

Miller, MM

Pollack, S

Boger, DL

机构：

[1] Scripps Res Inst, Res Inst, Dept Chem, La Jolla, CA 92037 USA

[2] Scripps Res Inst, Res Inst, Skaggs Inst Chem Biol, La Jolla, CA 92037 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2002年 / 124卷 / 38期

关键词：

D O I：

10.1021/ja027533n

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The scope of intramolecular Diels-Alder and a novel tandem Diels-Alder/1,3-dipolar cycloaddition cascade of 1,3,4-oxadiazoles is disclosed. In the cases examined, the tandem cycloadditions construct three new rings with formation of four new C-C bonds and set all six stereocenters about a central six-membered ring in a single step including three contiguous and four total quaternary centers without a trace of a second diastereomer. Copyright © 2002 American Chemical Society.

引用

页码：11292 / 11294

页数：3

共 32 条

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[2]

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