ATP synthase: an electrochemical transducer with rotatory mechanics

被引：410

作者：

Junge, W

Lill, H

Engelbrecht, S

机构：

[1] Universität Osnabrück, FB Biologie/Chemie, Abt. Biophysik

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1997年 / 22卷 / 11期

关键词：

D O I：

10.1016/S0968-0004(97)01129-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

ATP synthase (F0F1-ATPase) uses proton-or sodium-motive force to produce ATP from ADP and P-i. Three lines of experiment have recently demonstrated large-scale intersubunit rotation during ATP hydrolysis by F-1. We discuss how ion flow through the membrane-intrinsic portion, F-0, may generate torque and how this might be transmitted between stator and rotor to finally expel spontaneously formed ATP from F-1 into water.

引用

页码：420 / 423

页数：4

共 46 条

[1] STRUCTURE AT 2.8-ANGSTROM RESOLUTION OF F1-ATPASE FROM BOVINE HEART-MITOCHONDRIA
ABRAHAMS, JP
LESLIE, AGW
LUTTER, R
WALKER, JE
[J]. NATURE, 1994, 370 (6491) : 621 - 628
[2] PROTON CHANNEL OF THE CHLOROPLAST ATP SYNTHASE, CF0 - ITS TIME-AVERAGED SINGLE-CHANNEL CONDUCTANCE AS FUNCTION OF PH, TEMPERATURE, ISOTOPIC AND IONIC MEDIUM COMPOSITION
ALTHOFF, G
LILL, H
JUNGE, W
[J]. JOURNAL OF MEMBRANE BIOLOGY, 1989, 108 (03) : 263 - 271
[3] ZERO-LENGTH CROSS-LINKING BETWEEN SUBUNITS DELTA AND I OF THE H+-TRANSLOCATING ATPASE OF CHLOROPLASTS
BECKERS, G
BERZBORN, RJ
STROTMANN, H
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1992, 1101 (01) : 97 - 104
[4] Berg H. C., 1993, RANDOM WALKS BIOL
[5] H+/ATP coupling ratio at the unmodulated CF0CF1-ATP synthase determined by proton flux measurements
Berry, S
Rumberg, B
[J]. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, 1996, 1276 (01): : 51 - 56
[6] BIRKENHAGER R, 1995, EUR J BIOCHEM, V230, P58, DOI 10.1111/j.1432-1033.1995.0058i.x
[7] Boyer P.D., 1981, ENERGY COUPLING PHOT, P231
[8] THE BINDING CHANGE MECHANISM FOR ATP SYNTHASE - SOME PROBABILITIES AND POSSIBILITIES
BOYER, PD
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1993, 1140 (03) : 215 - 250
[9] THE BACTERIAL FLAGELLAR MOTOR
CAPLAN, SR
KARAIVANOV, M
[J]. INTERNATIONAL REVIEW OF CYTOLOGY - A SURVEY OF CELL BIOLOGY, VOL 147, 1993, 147 : 97 - 164
[10] ROTATION OF SUBUNITS DURING CATALYSIS BY ESCHERICHIA-COLI F1-ATPASE
DUNCAN, TM
BULYGIN, VV
ZHOU, Y
HUTCHEON, ML
CROSS, RL
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (24) : 10964 - 10968

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