Imaging of arsenic traces in human hair by nano-SIMS 50

被引：32

作者：

Audinot, JN

Schneider, S

Yegles, M

Hallegot, P

Wennig, R

Migeon, HN

机构：

[1] Ctr Rech Publ Gabriel Lippmann, Lab Anal Mat, L-1511 Luxembourg, Luxembourg

[2] Ctr Univ, CRP Sante, Div Toxicol, Lab Natl Sante, L-1511 Luxembourg, Luxembourg

[3] LOreal Rech, F-93600 Aulnay Sous Bois, France

来源：

APPLIED SURFACE SCIENCE | 2004年 / 231卷

关键词：

arsenic; Nano-SIMS; hair; imaging;

D O I：

10.1016/j.apsusc.2004.03.192

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The nano-SIMS 50 allows ion imaging to be performed on microtomed hair cross-sections in order to determine the concentration and to localize the distribution of arsenic traces in hairs. Our study shows a linear relationship between the SIMS signal (As normalized with respect to CN) and the concentration determined by other analytical techniques. The advantages of SIMS imaging can be clearly proved by the capability to record quantitative distributions of As in the cross section. As a matter of fact, the nano-SIMS 50 images may allow differentiation between As located in the medulla, the cortex and the cuticle of the hair and thus distinguish between intoxication by indigestion and surface pollution of the sample. (C) 2004 Elsevier B.V. All rights reserved.

引用

页码：490 / 496

页数：7