Encapsulation of purple membrane patches into polymeric nanofibers by electrospinning

被引:10
作者
Fischer, T
Hampp, NA [1 ]
机构
[1] Univ Marburg, Dept Chem, Inst Phys Chem, D-35032 Marburg, Germany
[2] Univ Marburg, Ctr Mat Sci, D-35032 Marburg, Germany
关键词
bacteriorhodopsin (BR); electrospinning; encapsulation; nanofiber;
D O I
10.1109/TNB.2004.828220
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The formation of beaded nanofibers containing purple membrane (PM) by electrospinning of polymer solutions is reported. Electrospinning is known as a versatile method to produce polymeric fibers with diameters on the nanometer scale. Embedding of particles significantly larger than the fiber diameter is unexpected because a breakdown of the spinning process is expected when microscaled particles in the polymer solution pass the nozzle. Presumably due to the flexibility of PM patches, the embedding of the membrane patches into the fibers becomes possible. Embedding into nanofibers may be an alternative to microencapsulation for biomolecules.
引用
收藏
页码:118 / 120
页数:3
相关论文
共 13 条
[1]   ELECTROSTATIC SPINNING OF ACRYLIC MICROFIBERS [J].
BAUMGARTEN, PK .
JOURNAL OF COLLOID AND INTERFACE SCIENCE, 1971, 36 (01) :71-+
[2]  
COFFEE RA, 1998, Patent No. 0912251
[3]  
Doshi J., 1994, THESIS U AKRON AKRON
[4]   INTERACTION OF PURPLE MEMBRANE WITH SOLVENTS .1. APPLICABILITY OF SOLUBILITY PARAMETER MAPPING [J].
EISENBACH, M ;
CAPLAN, SR ;
TANNY, G .
BIOCHIMICA ET BIOPHYSICA ACTA, 1979, 554 (02) :269-280
[5]  
Fong H, 1999, J POLYM SCI POL PHYS, V37, P3488, DOI 10.1002/(SICI)1099-0488(19991215)37:24<3488::AID-POLB9>3.0.CO
[6]  
2-M
[7]  
Formhals A, 1938, US Patent, Patent No. 2116942
[8]   Bacteriorhodopsin as a photochromic retinal protein for optical memories [J].
Hampp, N .
CHEMICAL REVIEWS, 2000, 100 (05) :1755-1776
[9]   Bacteriorhodopsin: mutating a biomaterial into an optoelectronic material [J].
Hampp, NA .
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2000, 53 (06) :633-639
[10]  
*HOECHST AKT, 2001, MOW POL