BILATERAL HAND TRANSPLANTATION: RESULT AT 20 MONTHS

被引：35

作者：

Cavadas, P. C. ^{[1
]}

Landin, L. ^{[1
]}

Ibanez, J. ^{[1
]}

机构：

[1] Clin Cavadas, Valencia 46021, Spain

来源：

JOURNAL OF HAND SURGERY-EUROPEAN VOLUME | 2009年 / 34E卷 / 04期

关键词：

hand transplantation; composite tissue allotransplantation; alemtuzumab; immunosuppression therapy; acute rejection; C4d; C4D DEPOSITION; ALLOGRAFT; FACE;

D O I：

10.1177/1753193409102898

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

On November 2006, a bilateral hand allotransplantation was performed for a 47-year-old female who had suffered radiocarpal amputations 28 years before. Technical aspects of the operation are detailed. Alemtuzumab induction, and triple therapy of tacrolimus, mycophenolate mofetil and prednisone were used to control rejection. The evolution of the result and functioning at 20 months are presented in detail. Two acute rejection episodes occurred and were successfully treated with steroids. In addition the patient developed a factitious visual disorder and a facial basal cell carcinoma. Functionally, at 20 months, the patient had a Hand Registry Functional Score of 69 (good), and a DASH score of 19.

引用

页码：434 / 443

页数：10

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