Global brain dysfunction in an infant with pyridoxine dependency: Evaluation with EEG, evoked potentials, MRI, and PET

被引：15

作者：

Shih, JJ

Kornblum, H

Shewmon, DA

机构：

[1] UNIV NEW MEXICO, CTR HLTH SCI, NEURODIAGNOST LAB, ALBUQUERQUE, NM 87131 USA

[2] UNIV CALIF LOS ANGELES, SCH MED, DEPT MOL & MED PHARMACOL, LOS ANGELES, CA USA

[3] UNIV CALIF LOS ANGELES, SCH MED, DEPT PEDIAT, LOS ANGELES, CA USA

[4] UNIV CALIF LOS ANGELES, SCH MED, DIV PEDIAT NEUROL, LOS ANGELES, CA USA

来源：

NEUROLOGY | 1996年 / 47卷 / 03期

关键词：

D O I：

10.1212/WNL.47.3.824

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Pyridoxine dependency often presents with intractable seizures in neonates and infants. We describe an infant with pyridoxine-dependent seizures and report the first PET and evoked potential results and EEG and MRI findings. All studies show either diffuse structural or functional abnormality. Our data suggest this coenzyme deficiency causes a generalized disease process.

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页码：824 / 826

页数：3

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